Deep responses following treatment with loncastuximab tesirine in patients with relapsed/refractory including those with high-risk, TP53-altered Waldenström macroglobulinemia
Independent Investigator-Initiated
Poster
ASH 2025
Consolidation with Loncastuximab Tesirine for Large B-cell Lymphoma Patients in Partial Response After CART: Planned Interim Futility Analysis of a Phase II Trial
Independent Investigator-Initiated
Poster
ASH 2025
Efficacy and Safety of Loncastuximab tesirine and Rituximab (Lonca-R) Followed by DA-R-EPOCH in Previously Untreated High-Risk DLBCL: Preliminary Results from UCDCC#303, a UCHMC Phase II Trial
Independent Investigator-Initiated
Oral Presentation
ICML 2025
Initial Results From LOTIS-7: A Phase 1b Study of Loncastuximab Tesirine Plus Glofitamab in Patients With Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
Poster
EHA 2025
Initial Results From LOTIS-7: A Phase 1b Study of Loncastuximab Tesirine Plus Glofitamab in Patients With Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
Poster
EHA 2025
Updated Safety Run-In Results From LOTIS-5: A Phase 3, Randomized Trial of Loncastuximab Tesirine With Rituximab Versus Immunochemotherapy in Patients With R/R DLBCL/HGBL
Oral Presentation
AACR 2025
Preclinical investigation of ADCT-242, a novel exatecan-based antibody drug conjugate targeting Claudin-6, as single agent or in combination in ovarian and non-small lung cancer models
Poster
AACR 2025
Preclinical development of ADCT-241, a novel exatecan-based antibody-drug conjugate targeting PSMA for the treatment of prostate cancer
Poster
AACR 2025
HuB14-VA-PL2202, a novel antibody-drug conjugate targeting ASCT2, a novel ADC target over-expressed in both solid and hematological cancers
Poster
ASH 2024
A Phase 2 Study of Loncastuximab Tesirine Plus Mosunetuzumab In Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Independent Investigator-Initiated
Poster
ASH 2024
Limited Duration Loncastuximab Tesirine Induces a High Rate of Complete Responses in Patients with Relapsed/Refractory Marginal Zone Lymphoma – Report of First Planned Interim Futility Analysis of a Multicenter Phase II Study
Independent Investigator-Initiated
Poster
ASH 2024
Loncastuximab Tesirine in Combination with Venetoclax Is Safe and Shows Efficacy in Patients with Relapsed/Refractory Non Hodgkin Lymphoma
Independent Investigator-Initiated
Poster
ASH 2024
A phase II trial of loncastuximab tesirine in patients with previously treated Waldenström macroglobulinemia
Independent Investigator-Initiated
Oral Presentation
ASH 2024
Loncastuximab Tesirine with Rituximab Induces Robust and Durable Complete Metabolic Responses in High-Risk Relapsed/Refractory Follicular Lymphoma
Independent Investigator-Initiated
Poster
CTOS 2024
Quantitative Systems Pharmacology Modeling of Mipasetamab Uzopterine Integrates Knowledge and Defines Dosing Strategy for Patients With Sarcoma
Poster
ACoP 2024
Quantitative Systems Pharmacology Modeling of Loncastuximab Tesirine Combined With Mosunetuzumab and Glofitamab Helps Guide Dosing for Patients With DLBCL
Poster
EORTC-NCI-AACR 2024
Preclinical characterization of NaPi2b-PL2202, a novel exatecan-based antibody drug conjugate
Poster
PPLC 2024
Phase 1b Open-Label Study Of Loncastuximab Tesirine In Combination With Other Anticancer Agents In Patients With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (LOTIS-7)
Poster
PPLC 2024
Quantitative Systems Pharmacology Model Predicts Combination Activity of CD19-Targeted Loncastuximab Tesirine Codosed With a CD20/CD3 T-cell Bispecific (Epcoritamab) in Diffuse Large B-cell Lymphoma
Poster
ASCO 2024
LOTIS-5, an Ongoing, Phase 3, Randomized Study of Loncastuximab Tesirine With Rituximab (Lonca-R) Versus Immunochemotherapy in Patients With R/R DLBCL
Poster
AACR 2024
Quantitative systems pharmacology modeling of loncastuximab tesirine combined with mosunetuzumab and glofitamab helps guide dosing for patients with DLBCL
Poster
AACR 2024
Preclinical anti-tumorigenic evaluation of AXL antibody-drug-conjugate in an adenoid cystic carcinoma cell line xenograft model
Independent
Poster
AACR 2024
Phase 1b Trial Mipasetamab Uzoptirine (ADCT-601-102) dose escalation in patients with advanced bone and soft tissue sarcomas
Poster
AACR 2024
Preclinical development of a novel camptothecin-based antibody-drug conjugate targeting solid tumors expressing Claudin-6
Poster
AACR 2024
Preclinical development of NaPi2b-PL2202, a novel camptothecin-based antibody-drug conjugate targeting solid tumors expressing NaPi2b
Poster
Tandem 2024
Limited duration loncastuximab with rituximab induces high complete response rate in high-risk relapsed/refractory follicular lymphoma – A phase 2 study
Independent Investigator-Initiated
Poster
Tandem 2024
Real-World Clinical Effectiveness of Loncastuximab Tesirine Monotherapy for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma Following Chimeric Antigen T Cell Therapy in the US
Poster
ASH 2023
A Phase II Study of Loncastuximab Tesirine As Consolidation Strategy in Patients with LBCL in PR at Day 30 after CAR T-Cell Therapy
Poster
ASH 2023
Hematopoietic Stem Cells Expressing Engineered CD45 Enable a Near Universal Targeted Therapy for Hematologic Diseases
Poster
ASH 2023
A Global Study of Novel Agents in Paediatric and Adolescent Relapsed and Refractory B-cell Non-Hodgkin Lymphoma (Glo-BNHL)
Poster
ASH 2023
Early and Sustained Circulating Tumor DNA Response Dynamics after Loncastuximab Tesirine for Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Poster
ASH 2023
Loncastuximab Tesirine Demonstrated Substantial Single-agent Efficacy and Manageable Safety Profile in Heavily Pretreated Chinese Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
Oral Presentation
ASH 2023
Limited duration loncastuximab with rituximab induces high complete response rate in high-risk relapsed/refractory follicular lymphoma – A phase 2 study
Independent Investigator-Initiated
Poster
ACCP 2023
A Clinical Quantitative Systems Pharmacolgy Framework Describing Loncastuximab Tesirine Distribution and the Exploration of Patient Outcomes From the LOTIS-2 Clinical Trial in Patients with B-cell Lymphomas
Poster
SOHO 2023
Phase 1b open-label study of loncastuximab tesirine in combination with other anticancer agents in patients with relapsed/refractory B-cell non-Hodgkin lymphoma (LOTIS-7)
Independent Investigator-Initiated
Poster
SOHO 2023
Updated Results of the Safety Run-In of the Phase 3 LOTIS-5 Trial: Novel Combination of Loncastuximab Tesirine With Rituximab (Lonca-R) Versus Immunochemotherapy in Patients With R/R DLBCL
Oral Presentation
ICML 2023
Long-Term Responses With Loncastuximab Tesirine: Updated Results From LOTIS-2, the Pivotal Phase 2 Study of Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Oral Presentation
ICML 2023
Long-Term Responses With Loncastuximab Tesirine: Updated Results From LOTIS-2, the Pivotal Phase 2 Study of Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Poster
EHA 2023
Long-Term Responses With Loncastuximab Tesirine: Updated Results From LOTIS-2, the Pivotal Phase 2 Study of Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Poster
ASCO 2023
Phase 1b open-label study of loncastuximab tesirine in combination with other anticancer agents in patients with relapsed/refractory B-cell non-Hodgkin lymphoma (LOTIS-7)
Poster
AACR 2023
Discovery of plasma protein biomarkers associated with overall survival in R/R DLBCL patients treated with loncastuximab tesirine
Poster
AACR 2023
Preclinical development of ADCT-212, a PSMA-targeted antibody-drug conjugate employing the pyrrolobenzodiazepine dimer SG2000 for PSMA-expressing cancers
Poster
AACR 2023
Preclinical development of ADCT-211, a novel pyrrolobenzodiazepine dimer-based antibody-drug conjugate targeting solid tumors expressing IL13RA2
Poster
AACR 2023
A Phase 1/2 Randomized Study of Imvotamab Monotherapy and in Combination with Loncastuximab Tesirine in Relapsed/Refractory Non-Hodgkin Lymphomas
Oral Presentation
ASH 2022
ADCT-602, a CD22 Targeting Antibody Drug Conjugate Bound to PBD Toxin in Adult Patients with Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia A Phase 1 Trial
Independent
Oral Presentation
ASH 2022
Real‐World Effectiveness and Economic Impact Associated with Chimeric Antigen Receptor T‐cell Therapy Among Older Patients with Relapsed/Refractory Diffuse Large B‐Cell Lymphoma in US
Poster
ASH 2022
CD25, Soluble CD25, and CCL17 as Potential Predictors of Clinical Response to Camidanlumab Tesirine in Patients With R/R Classical HL
Poster
ASH 2022
CD19 Expression by IHC Alone Is Not a Predictor of Response to Loncastuximab Tesirine: Results From LOTIS-2 and Quantitative Systems Pharmacology Modeling
Poster
ASH 2022
Development of Anti-CD45 Antibody Drug Conjugates As Targeted Conditioning Agents for Transplantation/Gene Therapy with Potent Anti-Leukemic Properties. “is not available at this time”
Poster
ASH 2022
Real-world Outcomes in Relapse/Refractory DLBCL Patients Who Received Polatuzumab Vedotin Plus Bendamustine and Rituximab or Tafasitamab Plus Lenalidomide by Line of Therapy
Poster
ASH 2022
A Phase 2, Open-Label Study of Loncastuximab Tesirine in Combination With Rituximab in Previously Untreated Unfit/Frail Patients With DLBCL (LOTIS-9)
Poster
ASH 2022
Exploratory Analysis of Factors Influencing Efficacy and Safety of Camidanlumab Tesirine: Data From the Open-Label, Multicenter, Phase 2 Study of Patients With R/R cHL
Poster
ASH 2022
Identification of predictive biomarkers for response of R/R DLBCL patients treated with loncastuximab tesirine using low-pass whole-genome cell-free DNA sequencing (cfDNA-WGS)
Poster
SOHO 2022
A Phase 2, Open-Label Study of Loncastuximab Tesirine in Combination With Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Patients With Diffuse Large B-cell Lymphoma (DLBCL) (LOTIS-9)
Poster
SOHO 2022
Health-Related Quality of Life and Tolerability in Patients With/Without Skin Toxicity During Loncastuximab Tesirine Treatment in a Phase 2 Clinical Trial (LOTIS-2)
Poster
SOHO 2022
Initial Safety Run-In Results of the Phase 3 LOTIS-5 Trial: Novel Combination of Loncastuximab Tesirine With Rituximab (Lonca-R) Versus Immunochemotherapy in Patients With R/R DLBCL
Poster
SOHO 2022
Long-Term Survival Projections of Loncastuximab Tesirine‒Treated Patients in Relapsed or Refractory Diffuse Large B-cell Lymphoma
Poster
SOHO 2022
Camidanlumab Tesirine: Updated Efficacy and Safety in an Open-Label, Multicenter, Phase 2 Study of Patients With Relapsed or Refractory Classical Hodgkin Lymphoma (R/R cHL)
Oral Presentation
SOHO 2022
Camidanlumab tesirine: updated efficacy and safety in an open-label, multicenter, phase 2 study of patients with relapsed or refractory classical Hodgkin lymphoma (R/R cHL)
Oral Presentation
EHA 2022
Camidanlumab tesirine: updated efficacy and safety in an open-label, multicenter, phase 2 study of patients with relapsed or refractory classical Hodgkin lymphoma (R/R cHL)
Poster
EHA 2022
Health-Related Quality of Life and Tolerability of Loncastuximab Tesirine in High-Risk Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma Treated in a Phase 2 Clinical Trial (LOTIS-2)
Poster
EHA 2022
Real-World characteristics and clinical outcomes in relapse/refractory diffuse large B-Cell lymphoma patients who received CAR-T therapy
Poster
EHA 2022
Real-World characteristics and clinical outcomes in relapse/refractory diffuse large B-Cell lymphoma post CAR-T failure
Poster
ASCO 2022
First-in-Human, Phase 1, Open-Label, Dose-Escalation Study of ADCT-901 as Monotherapy in Patients With Select Advanced Solid Tumors
Poster
ASCO 2022
Phase 3 Randomized Study of Loncastuximab Tesirine in Combination With Rituximab (Lonca-R) Versus Immunochemotherapy in Patients With R/R DLBCL LOTIS-5
Poster
ONS 2022
Onset, Duration, and Management of Edema and Effusion in Patients Treated With Loncastuximab Tesirine for R/R DLBCL: Updated Results From the LOTIS-2 Clinical Trial
Poster
ONS 2022
Characterization and Management of Cutaneous Reactions in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma Treated With Loncastuximab Tesirine in the LOTIS-2 Trial
Poster
AACR 2022
Effect of Camidanlumab Tesirine (Cami) as Monotherapy and in Combination With Pembrolizumab (PEM) on the Immune Cell Profile in Patients With Selected Advanced Solid Tumors
Poster
AACR 2022
Mechanistic studies investigating the synergistic combination of Loncastuximab Tesirine and Ibrutinib in pre-clinical models of B-Cell non-Hodgkin lymphoma
Poster
AACR 2022
AXL as a therapeutic target in adenoid cystic carcinoma: preclinical evaluation of AXL targeting antibody-drug conjugate (ADCT-601)
Poster
NCCN 2022
Health-Related Quality of Life, Symptoms, and Tolerability of Loncastuximab Tesirine in Older Versus Younger Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma Treated in a Phase 2 Clinical Trial (LOTIS-2)
Poster
HOPA 2022
A Pooled Safety Analysis of Loncastuximab Tesirine in R/R DLBCL in the LOTIS Clinical Trial Program: Incidence, Onset, and Management of Myelosuppression
Poster
ASH 2021
Clinical Characteristics and Responses of Patients with Relapsed or Refractory High‐Grade B‐Cell Lymphoma Treated with Loncastuximab Tesirine in the LOTIS‐2 Clinical Trial
Poster
ASH 2021
Combination of Loncastuximab Tesirine and Polatuzumab Vedotin Shows Increased Anti-Tumor Activity in Pre-Clinical Models of Non-Hodgkin Lymphoma
Poster
ASH 2021
CD19-mediated DNA Damage Boost in Lymphoma Cells Treated with Loncastuximab Tesirine in Combination with PARP Inhibitors
Oral Presentation
ASH 2021
Planned Interim Analysis of a Phase 2 Study of Loncastuximab Tesirine Plus Ibrutinib in Patients with Advanced Diffuse Large B‐Cell Lymphoma (LOTIS‐3)
Poster
ASH 2021
A Phase 1 Trial of ADCT-602, a CD22 Targeting Antibody Drug Conjugate Bound to PBD Toxin in Adult Patients with Relapsed or Refractory CD22+ B-Cell Acute Lymphoblastic Leukemia
Independent
Poster
ASH 2021
Clinical Characteristics and Responses of Patients With Relapsed or Refractory High-Grade B-Cell Lymphoma Treated With Loncastuximab Tesirine in the LOTIS-2 Clinical Trial
Poster
ASH 2021
The Anti-CD19 Antibody-Drug Conjugate Loncastuximab Tesirine Achieved Responses in Patients With Diffuse Large B-Cell Lymphoma Who Relapsed After Anti-CD19 CAR T-Cell Therapy
Independent
Poster
ASH 2021
Phase 1 Trial of ADCT-602, a CD22 Targeting ADC Bound to PBD Toxin in Adult Patients With RR CD22+ B-Cell ALL
Poster
AMCP Nexus 2021
Budget Impact Model for Loncastuximab Tesirine-lpyl in the Treatment of Relapsed/Refractory Diffuse Large B-cell Lymphoma
Poster
SOHO 2021
Incidence, onset, and management of myelosuppression in patients treated with loncastuximab tesirine for R/R DLBCL in a pooled safety analysis
Oral Presentation
SOHO 2021
LOTIS-2 follow-up analysis: Updated results from a Phase 2 study of loncastuximab tesirine in relapsed or refractory diffuse large B-Cell lymphoma
Poster
SOHO 2021
Incidence, onset, and management of edema and effusion in patients treated with loncastuximab tesirine for R/R DLBCL in the LOTIS clinical trial program
Poster
ICML 2021
Clinical activity of loncastuximab tesirine plus ibrutinib in non-Hodgkin lymphoma: Updated LOTIS-3 Phase 1 results
Oral Presentation
ICML 2021
Camidanlumab tesirine efficacy and safety in an open-label, multicenter, Phase 2 study of patients with relapsed or refractory classical Hodgkin lymphoma (R/R cHL)
Poster
ICML 2021
LOTIS-2 follow-up analysis: Updated results from a Phase 2 study of loncastuximab tesirine in relapsed or refractory diffuse large B-Cell lymphoma
Poster
ICML 2021
A Phase 3 randomized study of loncastuximab tesirine plus rituximab vs immunochemotherapy in patients with relapsed/refractory diffuse large B-Cell lymphoma — LOTIS-5
Poster
ICML 2021
A Phase 2 randomized study of loncastuximab tesirine (Lonca) vs idelalisib in patients with relapsed or refractory (R/R) follicular lymphoma (FL) — LOTIS-6
Poster
EHA 2021
Duration of Response to Loncastuximab Tesirine in Relapsed/Refractory Diffuse Large B-cell Lymphoma by Demographic and Clinical Characteristics: Subgroup Analyses from LOTIS-2
Poster
EHA 2021
Characteristics and Outcomes in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma Who Received ≥3 Lines of Therapies
Poster
ASCO 2021
A Phase 1b, Open-Label, Dose-Escalation Study to Evaluate Camidanlumab Tesirine (Cami) as Monotherapy in Patients with Advanced Solid Tumors
Poster
ASCO 2021
Duration of Response to Lonca RR DLBCL by Demographic Subgroup Analysis from LOTIS
Poster
ASCO 2021
Phase 3 Randomized Study of Lonca plus Rituximab versus Immunochemotherapy in Patients with RR DLBCL LOTIS
Poster
ISPOR 2021
Treatment-Related Costs of Pharmacologic Regimens for Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL) Who Have Received Two or More Prior Lines of Therapies
Poster
AACR 2021
Relationship Between Exposure and Safety/Efficacy of Loncastuximab Tesirine in B-cell Non-Hodgkin Lymphoma
Poster
AACR 2021
Integrated Population Modeling of Loncastuximab Tesirine (Lonca) Exposure in B-cell Non-Hodgkin Lymphoma (B-NHL)
Poster
ASH 2020
Characteristics and Treatment Patterns of Patients with Relapsed/Refractory Diffuse Large B-cell Lymphoma Who Received ≥3 Lines of Therapies in Post CAR-T Era
Poster
ASH 2020
Interim Results of Loncastuximab Tesirine Combined With Ibrutinib in Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma (LOTIS-3)
Poster
ASH 2020
Pharmacokinetic and Pharmacodynamic Correlates From the Phase 1 Study of Camidanlumab Tesirine (Cami) in Patients With Relapsed or Refractory Hodgkin Lymphoma and Non-Hodgkin Lymphoma
Poster
ASH 2020
Combination of Camidanlumab Tesirine, a CD25-Targeted ADC, with Gemcitabine Elicits Synergistic Anti-Tumor Activity in Preclinical Tumor Models
Poster
ASH 2020
Preliminary Results of a Phase 2 Study of Camidanlumab Tesirine (Cami), a Novel Pyrrolobenzodiazepine-Based Antibody-Drug Conjugate, in Patients With Relapsed or Refractory Hodgkin Lymphoma
Poster
ASH 2020
Analysis of ADCT-602 Pre-Clinical Activity in B-Cell Lymphoma Models and Identification of Potential Biomarkers for Its Activity
Poster
ASH 2020
Safety and Antitumor Activity Study Evaluating Loncastuximab Tesirine and Rituximab Versus Immunochemotherapy in Diffuse Large B-Cell Lymphoma
Poster
ASH 2020
Efficacy and Safety of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Poster
SITC 2020
A Tregs-depleting CD25-targeted antibody-drug conjugate synergizes with tumor-targeted radiotherapy and systemic interleukin-2 in pre-clinical models of solid cancers
Poster
ESMO 2020
First-in-Human Study of Camidanlumab Tesirine (ADCT-301, Cami), an anti-CD25 Targeted Therapy in Patients (Pts) with Advanced Solid Tumors: Pharmacokinetics (PK) and Biomarker Evaluation
Poster
EHA 2020
Interim results of a phase 1/2 study of loncastuximab tesirine (Lonca) combined with ibrutinib in advanced diffuse large B-cell lymphoma (DLBCL) or mantle cell lymphoma (MCL)
Oral Presentation
EHA 2020
Initial Results of a Phase 2 Study of Loncastuximab Tesirine, a Novel Pyrrolobenzodiazepine-Based Antibody-Drug Conjugate, in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Poster
ASH 2019
Interim Futility Analysis of a Phase 2 Study of Loncastuximab Tesirine, a Novel Pyrrolobenzodiazepine-Based Antibody-Drug Conjugate, in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Poster
SITC 2019
Pre-clinical characterization of the mechanism of action of a CD25-targeted pyrrolobenzodiazepine dimer-based antibody-drug conjugate targeting regulatory T cells in solid cancers
Poster
ESMO 2019
A Phase 1, Open-label, Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-601 in Patients with Advanced Solid Tumors
Poster
ICML 2019
The anti-CD25 antibody-drug conjugate camidanlumab tesirine (ADCT-301) presents a strong preclinical activity both as single agent and in combination in lymphoma cell lines
Oral Presentation
ICML 2019
Analysis of Clinical Determinants Driving Safety and Efficacy of Camidanlumab Tesirine (ADCT-301, Cami) in Relapsed/Refractory (R/R) Classical Hodgkin Lymphoma (cHL)
Oral Presentation
ICML 2019
The Antibody-Drug Conjugate (ADC) Loncastuximab Tesirine (ADCT 402) Targeting CD19 Shows Strong in vitro Anti-Lymphoma Activity Both As Single Agents and in Combination
Oral Presentation
ICML 2019
Analysis of Efficacy and Safety of Loncastuximab Tesirine (ADCT-402) by Demographic and Clinical Characteristics in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Poster
AACR 2019
Pre-clinical characterization of 3A4-PL1601, a novel pyrrolobenzodiazepine (PBD) dimer-based antibody-drug conjugate (ADC) directed against KAAG1-expressing malignancies
Poster
ASH 2018
Phase 1 Study of ADCT-301 (Camidanlumab Tesirine), a Novel Pyrrolobenzodiazepine-Based Antibody Drug Conjugate, in Relapsed/Refractory Classical Hodgkin Lymphoma
Poster
SITC 2018
A CD25-targeted pyrrolobenzodiazepine dimer-based antibody-drug conjugate shows potent anti-tumor activity in pre-clinical models of solid tumors either alone or in combination with a PD-1 inhibitor
Pre-clinical activity of ADCT-601, a novel pyrrolobenzodiazepine (PBD) dimer-based antibody-drug conjugate (ADC) targeting AXL-expressing tumors
Poster
ASH 2017
Results from an Ongoing Phase 1 Study Indicate ADCT-301 (Camidanlumab Tesirine) Is Well Tolerated in Patients with Relapsed or Refractory CD25-Positive Acute Leukemia
Poster
ASH 2017
Elucidating Exposure-Response (Safety and Efficacy) of ADCT-402 (Loncastuximab Tesirine), a Novel Pyrrolobenzodiazepine-Containing Antibody Drug Conjugate, for Recommended Phase 2 Dose Determination in Patients with Relapsed or Refractory Non-Hodgkin Lymphoma
Poster
AACR 2017
Characterization of the mechanism of action, pharmacodynamics and preclinical safety of ADCT-402, no. 51 a pyrrolobenzodiazepine (PBD) dimer-containing antibody-drug conjugate (ADC) targeting CD19-expressing hematological malignancies
Poster
ASH 2016
ADCT-602 (hLL2-cys-PBD), a new site-specifically conjugated, pyrrolobenzodiazepine (PBD) dimer-based antibody drug conjugate (ADC) targeting CD22-expressing B-cell malignancies
Poster
ASCO 2016
A phase 1 dose-escalation study to evaluate the tolerability, safety, pharmacokinetics, and antitumor activity of ADCT-402 in patients with relapsed or refractory B-Cell lineage non-Hodgkin lymphoma (B-NHL)
Poster
AACR 2015
Pre-clinical Activity of hLL2-PBD, a Novel Anti-CD22 Antibody-Pyrrolobenzodiazepine (PBD) Conjugate in Models of Non-Hodgkin Lymphoma
This information is provided for educational purposes only and should not replace advice from your healthcare provider. ADC Therapeutics does not offer medical advice or make treatment recommendations. Talk to your doctor to learn whether loncastuximab tesirine may be right for your situation.
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